Meta-Data and Interface Synthesis Techniques for Improving Design Productivity in Reconfigurable Computing

This paper demonstrates improvements in design productivity for reconfigurable computing which are accomplished through a novel IP reuse strategy. It presents a set of extensions to the IP-XACT XML specification that define the temporal behavior of cores and describes how these extensions are used in the Ogre synthesis system to simplify design complexity and thereby reduce design time. Design productivity improvement is demonstrated by reducing design time for software radio designs from days to hours

Meta-Data-Enabled Reuse of Dataflow Intellectual Property for FPGAs

This paper demonstrates the ability to reuse arbitrary IP as primitive cores in architectural synthesis algorithms for FPGA by encapsulating these IP in meta-data. This metadata is represented as a set of extensions to the IP-XACT XML specification and defines the high-level data types and the temporal behavior of IP. This paper describes how these extensions are used in the Ogre synthesis system to facilitate automatic synthesis of control and interface logic for homogeneous synchronous dataflow (H-SDF) designs

Generation of maximum spin entanglement induced by cavity field in quantum-dot systems

Equivalent-neighbor interactions of the conduction-band electron spins of quantum dots in the model of Imamoglu et al. [Phys. Rev. Lett. 83, 4204 (1999)] are analyzed. Analytical solution and its Schmidt decomposition are found and applied to evaluate how much the initially excited dots can be entangled to the remaining dots if all of them are initially disentangled. It is demonstrated that the perfect maximally entangled states (MES) can only be generated in the systems of up to 6 dots with a single dot initially excited. It is also shown that highly entangled states, approximating the MES with a good accuracy, can still be generated in systems of odd number of dots with almost half of them being excited. A sudden decrease of entanglement is observed by increasing the total number of dots in a system with a fixed number of excitations.Comment: 6 pages, 7 figures, to appear in Phys. Rev.

Dementia Revealed: Novel Chromosome 6 Locus for Late-Onset Alzheimer Disease Provides Genetic Evidence for Folate-Pathway Abnormalities

Genome-wide association studies (GWAS) of late-onset Alzheimer disease (LOAD) have consistently observed strong evidence of association with polymorphisms in APOE. However, until recently, variants at few other loci with statistically significant associations have replicated across studies. The present study combines data on 483,399 single nucleotide polymorphisms (SNPs) from a previously reported GWAS of 492 LOAD cases and 496 controls and from an independent set of 439 LOAD cases and 608 controls to strengthen power to identify novel genetic association signals. Associations exceeding the experiment-wide significance threshold () were replicated in an additional 1,338 cases and 2,003 controls. As expected, these analyses unequivocally confirmed APOE's risk effect (rs2075650, ). Additionally, the SNP rs11754661 at 151.2 Mb of chromosome 6q25.1 in the gene MTHFD1L (which encodes the methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein) was significantly associated with LOAD (; Bonferroni-corrected P = 0.022). Subsequent genotyping of SNPs in high linkage disequilibrium () with rs11754661 identified statistically significant associations in multiple SNPs (rs803424, P = 0.016; rs2073067, P = 0.03; rs2072064, P = 0.035), reducing the likelihood of association due to genotyping error. In the replication case-control set, we observed an association of rs11754661 in the same direction as the previous association at P = 0.002 ( in combined analysis of discovery and replication sets), with associations of similar statistical significance at several adjacent SNPs (rs17349743, P = 0.005; rs803422, P = 0.004). In summary, we observed and replicated a novel statistically significant association in MTHFD1L, a gene involved in the tetrahydrofolate synthesis pathway. This finding is noteworthy, as MTHFD1L may play a role in the generation of methionine from homocysteine and influence homocysteine-related pathways and as levels of homocysteine are a significant risk factor for LOAD development

The Physics of the B Factories

This work is on the Physics of the B Factories. Part A of this book contains a brief description of the SLAC and KEK B Factories as well as their detectors, BaBar and Belle, and data taking related issues. Part B discusses tools and methods used by the experiments in order to obtain results. The results themselves can be found in Part C

|Vub| from exclusive semileptonic B--> rho decays

We use Omnes representations of the form factors V, A_1 and A_2 for exclusive semileptonic B--&gt; rho decays, and apply them to combine experimental partial branching fraction information with theoretical calculations of the three formfactors to extract |Vub|. We find a slightly lower result, |Vub|=(2.8 +- 0.2)x10^{-3}, than the values extracted from exclusive semileptonic B--&gt;pi decays and using all other inputs in CKM fits. The disagreement is greater when we compare to the result extracted from inclusive B -&gt; X_u l nu decays<br/